Endocrine Abstracts

Introduction: Hypovitaminosis D is a biochemical change with high prevalence among the population, especially in obese patients. Its function more known relates to bones metabolism, although recently, many functions have been described.Methods: A descriptive cross-sectional study, which included women over 18 years old with BMI equal or superior of 25 kg/m2. Anthropometric measurements were obtained: weight, height, BMI, waist circumference, h...

Introduction: Obese persons may have low vitamin D levels due to behaviors (clothing, time outdoors) that can reduce synthesis of vitamin D. In overweight and obese individuals there are limited quantitative data regarding relationships among serum 25(OH)D, time spent outdoors, sun exposure, and clothing worn.Methods: We assessed environmental and behavioral factors that contribute to cutaneous synthesis of serum 25(OH)D in 63 overweight and obese indivi...

The extracellular matrix protein laminin forms polymers both in vivo and in vitro. Acidification of pH leads to the formation of an artificial polymer with biomimetical properties, named poly-laminin (polyLM). Follicular cells in the thyroid are in close contact with laminin, but their response to this important extracellular signal is still poorly understood. Thyroid PCCL3 epithelial cells cultivated either on glass, regular laminin (LM) or laminin previously po...